Protein interactions

Name : Brian Murray
Department : Chemical and Biological Engineering
Topic : Protein-Protein Interactions
Date : November 24,2015

Social Value

 The research we learned about is important because it affects many of our lives. Understanding
how proteins interact with each other is extremely important in understanding protein based
diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and many more. The better we
understand such diseases, the closer we get to being able to combat and defeat them.


Government Connection

The fingerprint experiment connects to government because when a crime takes place, police
often use forensics to detect fingerprints at the scene. Fibril detection is similar to fingerprint
detection because it breaks down to the organic chemistry of each thing.

Economics Connection
●
If the detection is used in health care, it will have to be done at a cost that is available to
patients. This relates to “Economies of Scale.”

● Resistance cost
Antibiotics
are becoming less effective and it’s costing the US $2134
billion a year to fix it. If we can develop the solution, it can save billions in the budget (and many lives)

Guest Connections
●Ullal and Palermo proteins
are also polymers
● Lindhardt Relating
to health care
● Silva Polymers
● Borten Economies
of Scale

Terms/Concepts
●Protein Linear
chain of amino acids
● Neurofibrillary Tangles The
reason why some diseases occur
● Amyloid Plaques - build up of tangles; obvious in autopsy of diseasesd.
● ABeta
The
protein responsible for Alzheimer’s Disease
● Amyloid Fibers
When
the ABetas
stick together
● Antimicrobial Resistance
Bacteria
start becoming tolerant to medicines
● Antimicrobial Peptides
one possible olution
to eliminating Antimicrobial Resistance